Quantitative tissue analysis

From biomedical images to quantitative biomarkers

PioneerBio turns microscopy into measurement. Our AI platform goes beyond segmentation — multi-scale morphometrics and spatial analysis build reproducible "architectural fingerprints" of your tissue, so findings rest on numbers rather than impressions.

Developed with researchers at Linköping University · Drag the image to see the analysis

transmission electron micrograph analysis complete
Micrograph with every structure delineated in teal by the platform Raw transmission electron micrograph RAWDETECTED
Transmission electron micrograph of avian feather barbules; melanosomes segmented on the PioneerBio platform (teal).

In research & teaching with

From qualitative art to quantitative science

Tissue analysis has been limited by slow, subjective manual methods

For decades, pathology and morphometry have depended on what a trained eye can grade and count. Every step of our platform replaces an impression with a measurement — the same image, the same protocol, the same number, every time.

Manual counting, hours per image Automated segmentationThousands of structures delineated in minutes
Subjective visual grading Objective morphometricsSize, shape, and texture as calibrated values
Isolated observations Spatial architectureNeighbourhoods, gradients, and tissue-level patterns
One-off analyses Reproducible pipelinesVersioned models with an auditable trail

How we work

One platform, from raw image to reportable result

An end-to-end workflow that keeps your data, your models, and your results in one auditable place.

01 — RESEARCH & SOLUTION

Frame the question, curate the data

We work from your images and your endpoint. Ground truth is annotated collaboratively in the platform, with roles and review built in.

projects · annotation · ground truth
02 — DESIGN & STRATEGY

Segment, measure, validate

GPU-accelerated models delineate every structure; multi-scale morphometrics and spatial statistics turn them into candidate biomarkers, validated against held-out data.

segmentation · morphometrics · validation
03 — GENERATE REPORT

Report and discover

Interactive results you can interrogate — per structure, per region, per cohort — and export as figures and tables ready for publication or filing.

dashboards · export · publication-ready

The platform

Built for measurement, not just detection

Segmentation is the first step, not the product. The platform is designed around what happens after the mask.

Multi-scale morphometrics

From sub-cellular texture to whole-tissue statistics — hundreds of calibrated features per structure, in real physical units.

Spatial architecture

Neighbourhood graphs, density maps and regional gradients capture how tissue is organised — not only what it contains.

Reproducible by design

Versioned models, pinned pipelines and a full audit trail — the same input gives the same answer next month, and you can prove it.

Made for collaboration

Projects, roles and shared annotation bring clinicians, biologists and analysts into one workspace — used in research and teaching today.

Teaching

Courses supported by PioneerBio infrastructure

Micro-module · 2.5 ECTS · Online

Introduction to AI-based biomedical image analysis for cell segmentation

Linköping University · ECIU University

View on ECIU Engage →
Challenge · 5 ECTS · Blended

AI-based biomedical image analysis for cell segmentation

Linköping University · ECIU University

View on ECIU Engage →

Grounded in peer review

Science first, product second

Our methods grow out of published research in quantitative microscopy and sensory biology — documented, cited, and open to scrutiny.

Featured on the issue cover · The Journal of Physiology

Robust coupling between the C-tactile afferent and the hair follicle in humans

Moore, Nikesjö, Bouchatta, Makdani, Hakizimana, Rousson, Duvernoy, McIntyre, Pehkonen, Fridberger, McGlone, Olausson, Nagi & Marshall
The Journal of Physiology 603(16): 4593–4608, 2025

Work with us

See your tissue in numbers

Bring a dataset and a question. In a 30-minute call we'll walk through what the platform can measure in your images — and what it would take to get there.